Known as the world’s “Strongest Creature”, Kaido of the Beasts is a powerful Zoan-type user who occupies Wano Country and is an Emperor of the New World. With his Mythical Zoan-Type Devil Fruit, the Uo Uo no Mi, Model: Seriyu, the Beast Pirates captain is undoubtedly one of the strongest pirates in all ofOne Piece.
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Though Kaido’s power has a vast reputation, it should be known that he’s been defeated and captured numerous times — 7 defeats and 18 captures, to be exact. As such, the New World Emperor is not immortal. Knowing that defeating him is entirely possible, it begs the question: how would one go about increasing that number of defeats, and what Devil Fruit abilities inOne Piecewould be best for such a task?
Updated on May 31, 2025, by By Rei Penber: Kaido’s Mythical Zoan Uo Uo no Mi, Model: Seiryu remains to be one of the strongest Devil Fruits in the story. Although the Devil Fruit has few weaknesses, there are ways other Devil Fruit powers can work their way around its defenses.
While 10 Devil fruits that can counter this fruit are already listed, there are quite a few others that fare well against the Yonko’s power as well, and these Devil Fruits are certainly in a league of their own.
15Hei Hei No Mi
Hei Hei no Mi is a Logia Devil Fruit wielded by former Marine Admiral, Aokiji. This Devil Fruit allows him to control ice at will, along with granting him the ability to freeze someone from the inside. So far, he has used it on several occasions, such as on Long Ring Long Island, where he almost killed Nico Robin upon seeing her.
This Devil Fruit can easily ignore the insanely powerful defense of Kaido by merely touching him. As seen during the Marineford arc, Aokiji was able to freeze Jozu’s arm even with his Kira Kira no Mi powers active. his Devil Fruit ability still being active.
14Hito Hito No Mi, Model: Daibutsu
Mythical Zoan Devil Fruitshave very unique abilities and Hito Hito no Mi, Model: Daibutsu is no different. This fruit its user to transform into a huge golden Buddha and heightens their physical strength, along with granting immense offensive powers. The offensive ability is granted in the form of shockwaves and is comparable to the quakes of Gura Gura no Mi, as evident from the Marineford arc where Blackbeard and Sengoku clashed.
Evidently, these shockwaves can easily penetrate Kaido’s scales and bypass all the defensive powers that his Devil Fruit offers to him. Furthermore, the full potential of this Devil Fruit hasn’t been seen yet, meaning there could be even greater abilities to use against Kaido.
13Suna Suna No Mi
Crocodile, one of the former Shichibukai, was introduced quite early during the Alabasta arc and wieldsthe Logia-type Devil Fruitcalled Suna Suna no Mi. This Devil Fruit grants him the ability to transform into and control sand at will.
Furthermore, it also gives him one of the most overpowered abilities in the story to date, which is the ability to dehydrate anyone with a touch of his right hand. Essentially, this Devil Fruit offers a one-hit kill that can even work against the Yonko Kaido.
12Goro Goro No Mi
Enel’s Goro Goro no Mi remains to be one of the most overpowered abilities in the story even now. It is a Logia-type Devil Fruit that grants him the power to control electricity and turn into it at will.
The Goro Goro no Mi has a tremendous power output capable of easily hurting some of the strongest characters such as Zoro and Sanji. The Goro Goro no Mi’s attacks can penetrate Kaido’s body without doing any external damage, making it quite useful against him.
11Jiki Jiki No Mi
Jiki Jiki no Mi isa Paramecia-type Devil Fruitwielded by Eustass Kidd. This fruit allows him to manipulate magnetic force at will. On the surface level, the power offered by this Devil Fruit doesn’t seem all that impressive but, as seen in the fight against Big Mom and Kaido, it can be extremely dangerous.
This Devil Fruit is capable of damaging Kaido by creating massive amounts of pressure to crush his internal organs. On the rooftop of Onigashima, Kid proved that his Devil Fruit was more than capable of hurting Kaido. Furthermore, His awakening made him even more dangerous when he fought Big Mom.
10Shibo Shibo No Mi
The Shibo Shibo no Mi lets the user wring out its victims and drains them of liquid, transferring the liquid into both the user and their weapon. Consumed by Charlotte Smoothie, this Devil Fruit’s ability can completely dry out living things, leaving them susceptible to dehydration-related injuries.
The benefit of this Devil Fruit’s abilities is that it can increase Smoothie’s size while simultaneously damaging her opponent. While this was detrimental when using it on her ship due to potentially crushing it, fighting Kaido on land would grant her zero limitations with her growth. Since Kaido is so large, growing larger through her ability would be beneficial as a means to match his physical power — plus, her growth would directly correlate to Kaido being weakened.
9Peto Peto No Mi
An anime-exclusive Devil Fruit, Breed’s Peto Peto no Mi allows him to control any living thing by forcing a collar onto them, subsequently turning them into his pet. Breed can give his pets demands and take full control of their bodies, but not their consciousness.
Though victims can temporarily resist commands through willpower, Breed can heighten his own physical power by placing a collar on himself and commanding himself to be stronger. Doing so, in combination with capturing Kaido, would hopefully grant him the power to take control over the Zoan-type user.
8Yami Yami No Mi
Every Devil Fruit user’s worst nightmare, Marshall D. Teach (Blackbeard) uses the Yami Yami no Mi’s darkness abilities to suck enemies into black holes. With victims trapped, Blackbeard can cause immense damage and nullify a Devil Fruit user’s abilities, which is disastrous to those who rely on their abilities heavily.
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Between the two Emperors (who are both powerful characters in the recentOne Piece: Pirate Warriors 4game), a fight would come down to Blackbeard’s ability abolishment. Though Kaido is a strong fighter regardless of his Devil Fruit, stacking up his flat combat skill against Blackbeard withtwoDevil Fruits would most likely result in a loss for Kaido.
7Ato Ato No Mi
While an unconventionally powerful Devil Fruit, the Ato Ato no Mi thrives in its ability to leave victims ineffective while trapped. Its user, Giolla, canturn people into visually stunning works of art, forcing them to trade their lives for Giolla’s artwork.
Though Giolla herself can be physically overwhelmed easily, this Devil Fruit ability is not one to be underestimated. It would only take immobilizing or distracting Kaido long enough for Giolla’s ability to take effect to leave him vulnerable, and Giolla would only need to concentrate on remaining conscious to keep Kaido as an art piece.
6Ope Ope No Mi
A popular Devil Fruit (used by a popular Devil Fruit user), the Ope Ope no Mi allows the user to create a “room” where they can manipulate the objects inside. Law can dismember limbs of enemies and rearrange them on different bodies, teleport himself and others, switch people’s souls, or expose organs while in the room.
Against Kaido, Law could prioritize dismemberment to weaken Kaido’s defenses. A particularly strategic move would be exposing Kaido’s heart and attacking it directly since he wouldn’t be able to use his abilities to protect it (as shown when Law used this to kill Monet, another Devil Fruit user). So long as Law can maintain stamina and keep Kaido within his room, he should prove a worthy adversary for the Emperor.
